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Cellular uptake of the MPEG-b-PMAA-YVO4:Eu NPs is evaluated by cell imaging assay, indicating that the NPs can be taken up rapidly and largely by cancerous or non-cancerous cells through an endocytosis mechanism.īiocompatibility Cell imaging Fluorescent probe YVO(4):Eu nanoparticle.Ĭopyright © 2015 Elsevier B.V. 11 Wang H, Yu M, Lin C K and Lin J 2006 Core/shell structured SiO2YVO4: D圓+/Sm3+ phosphor particles: Sol-gel preparation and characterization J. 95% cell viability can be achieved at the NPs concentration of 800 mgL(-1) after 24h of culture. In addition, the biocompatibility MPEG layer reduces the cytotoxicity of the nanoparticles effectively. The capping copolymer MPEG-b-PMAA improves the dispersibility of hydrophobic YVO4:Eu NPs in water, making the NPs stable under different conditions. Significant enhancement in luminescence intensity by MPEG-b-PMAA-YVO4:Eu NPs formation is observed. Core-shell structured SiO2YVO4:D圓+/Sm3+ phosphor particles: sol-gel preparation and characterization. In this paper, we present a comparative study for bulk, nanosized and YF 3 core-shelled europium doped YVO 4 by means of photoluminescence analysis (both steady state and time-resolved) in wide spectral range including vacuum ultraviolet spectral range. The nanocomposites have the advantage of high magnetic responsive and unique luminescence properties. For instance, recently it was demonstrated that core shell layers around YVO 4:Eu nanoparticles can significantly improve their luminescence efficiency,.
YVO4 YVO4 CORE SHELL SERIES
The MPEG-b-PMAA-YVO4:Eu NPs, with an average diameter of 24 nm, have a tetragonal structure and demonstrate luminescence in the red region, which lies in a biological window (optical imaging). A series of coreshell bifunctional magneticoptical YVO 4 :Ln 3+ Fe 3 O 4 (Ln 3+ Eu 3+ or Dy 3+ ) nanocomposites have been successfully synthesized via two-step method. A precise defined model is established according to analyzing the coefficients of pH and CEu% during the synthesis. The thickness of SiO2 shells was altered by changing the molar ratio of tetraethoxysilane (TEOS)/YVO4:Eu 3+. Factors including reaction time, reaction temperature, CEu% and pH are optimized for the preparation of the YVO4:Eu NPs. Comparing the luminescence processes of YVO4:Eu and core-shell YVO4YF3 nanocrystals with bulk-YVO4:Eu Shirmane, L. Multi-layer core-shell nanoparticles (YVO4:Nd3+/mSiO2/SiO2) consisting of silica cores (SiO2), mesoporous silica (mSiO2) intermediate layers, and Neodymium. The PMAA block attached tightly on the YVO4:Eu core forms the inner shell and the MPEG block forms the biocompatible outermost shell. The synthesis of YVO4:Eu core, which further makes MPEG-b-PMAA-YVO4:Eu NPs adapt for cell imaging, is guided by the model determined upon the evaluation of pH and CEu%. There are fairly energy transfer both core and core-shell nanoparticles.
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A novel nanoparticle with multilayer core-shell architecture for cell imaging is designed and synthesized by coating a fluorescent YVO4:Eu core with a diblock copolymer, MPEG-b-PMAA. Luminescence technique could prove the core-shell formation of YVO4 covered by SiO2.
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